Bergamot is a citrus fruit originally from southern Italy, from Calabria Jonica.

The AICAL Association proposes dissemination actions and continuous studies.

With simple traditional uses such as the intake of juice (Bergasterol) or powders (Bergastatina) they include the improvement of the immune response and cardiovascular function. There are a variety of phytochemicals that have been found in bergamot, including brutieridin and melitidin, as well as other flavonoids, flavones O-glucosides and C-glucosides.

Numerous clinical studies have shown that several forms of bergamot administered orally can reduce total cholesterol and low-density lipoprotein cholesterol. In vitro mechanistic studies have shown that bergamot polyphenols can alter the function of AMPK and pancreatic cholesterol ester hydrolase (pCEH). The use of bergamot used in multiple clinical studies has consistently shown that it is well tolerated and has no particular contraindications. This mini-review reports the clinical studies carried out with different forms of bergamot together with their effectiveness in reducing total cholesterol and LDL cholesterol in patients with hypercholesterolemia.

Keywords: #bergamotto, #brutieridina, #melitidina, #cholesterol, #antioxidant, #citrus #bergamia #naringenin
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